Protein synthesis in liver and extra-hepatic tissues after partial hepatectomy

Protein synthesis in liver and extra-hepatic tissues after partial hepatectomy.

Effects of partial hepatectomy on protein synthesis were defined in liver and extra-hepatic tissues of the mature rat. Studies were performed at 24 h and 48 h after surgery in the absence of the dietary input. Protein accretion in the regenerating liver preceded mitosis, but was accompanied by increases in RNA content and fractional rates of protein synthesis (ks). A positive relationship exist...

Liver protein synthesis after partial hepatectomy and acute stress.

Partial hepatectomy and acute stress (intraperitoneal injection of Celite) cause increases in the rates of synthesis of serum albumin and fibrinogen, proteins that are formed mainly or entirely by the liver. The rises in protein synthesis after removal of part of the liver differ kinetically from those after acute stress. In addition, only the response to partial hepatectomy is independent of t...

Hepatic Progenitors of the Liver and Extra-Hepatic Tissues

Regeneration of mouse liver after partial hepatectomy.

The rapidly growing liver tissue after partial hepatectomy has been used advantageously by in vestigators to study changes during accelerated growth and proliferation of cells (4, 7, 12, 15). Previous reports have been chiefly on rats. In many instances, pooled samples were taken for chemical data. In the present investigation a com prehensive study was made on individual samples of regeneratin...

Silymarin Accelerates Liver Regeneration after Partial Hepatectomy

Partial hepatectomy (PHx) is a liver regeneration physiological response induced to maintain homeostasis. Liver regeneration evolved presumably to protect wild animals from catastrophic liver loss caused by toxins or tissue injury. Silymarin (Sm) ability to stimulate liver regeneration has been an object of curiosity for many years. Silymarin has been investigated for use as an antioxidant and ...